Place half of the tortilla chips in a single layer in the air fryer basket making sure to overlap the chips so there are no gaps. Top the chips with half of the brisket, half of the cheese and half of the red onion.
Repeat the layers. Cook the nachos for 3-5 minutes or until cheese has melted and the brisket is heated through.
Remove from the basket and top with diced tomatoes, jalapenos, and cilantro.
Serve with salsa and sour cream if desired.
Video
Notes
If using fresh jalapenos, they can be added before cooking. If using pickled jalapenos, they can be added after cooking.